User profiles for Simon de Lusignan
Simon de LusignanProfessor of Primary Care and Clinical Informatics, University of Surrey Verified email at surrey.ac.uk Cited by 25806 |
[HTML][HTML] Interim findings from first-dose mass COVID-19 vaccination roll-out and COVID-19 hospital admissions in Scotland: a national prospective cohort study
Background The BNT162b2 mRNA (Pfizer–BioNTech) and ChAdOx1 nCoV-19 (Oxford–AstraZeneca)
COVID-19 vaccines have shown high efficacy against disease in phase 3 clinical …
COVID-19 vaccines have shown high efficacy against disease in phase 3 clinical …
[HTML][HTML] Risk factors for SARS-CoV-2 among patients in the Oxford Royal College of General Practitioners Research and Surveillance Centre primary care network: a …
Background There are few primary care studies of the COVID-19 pandemic. We aimed to
identify demographic and clinical risk factors for testing positive for severe acute respiratory …
identify demographic and clinical risk factors for testing positive for severe acute respiratory …
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
…, M Carstensen-Kirberg, AJM De Craen, S De Lusignan… - Nature, 2017 - nature.com
Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at
risk of developing type 2 diabetes, cardiovascular disease and related metabolic and …
risk of developing type 2 diabetes, cardiovascular disease and related metabolic and …
Using the Internet to conduct surveys of health professionals: a valid alternative?
Objective. The purpose of this study was to examine whether Internet-based surveys of
health professionals can provide a valid alternative to traditional survey methods. Methods. (i) …
health professionals can provide a valid alternative to traditional survey methods. Methods. (i) …
[HTML][HTML] First-dose ChAdOx1 and BNT162b2 COVID-19 vaccines and thrombocytopenic, thromboembolic and hemorrhagic events in Scotland
Reports of ChAdOx1 vaccine–associated thrombocytopenia and vascular adverse events
have led to some countries restricting its use. Using a national prospective cohort, we …
have led to some countries restricting its use. Using a national prospective cohort, we …
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control …
Background Indian Asians, who make up a quarter of the world's population, are at high risk
of developing type 2 diabetes. We investigated whether DNA methylation is associated with …
of developing type 2 diabetes. We investigated whether DNA methylation is associated with …
[HTML][HTML] Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label …
Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in
patients not admitted to hospital, but effectiveness in high-risk individuals is unknown. We …
patients not admitted to hospital, but effectiveness in high-risk individuals is unknown. We …
[HTML][HTML] Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million …
Background Current UK vaccination policy is to offer future COVID-19 booster doses to
individuals at high risk of serious illness from COVID-19, but it is still uncertain which groups of …
individuals at high risk of serious illness from COVID-19, but it is still uncertain which groups of …
The use of routinely collected computer data for research in primary care: opportunities and challenges
S de Lusignan, C van Weel - Family practice, 2006 - academic.oup.com
Introduction. Routinely collected primary care data has underpinned research that has helped
define primary care as a specialty. In the early years of the discipline, data were collected …
define primary care as a specialty. In the early years of the discipline, data were collected …
[HTML][HTML] Low levels of respiratory syncytial virus activity in Europe during the 2020/21 season: what can we expect in the coming summer and autumn/winter?
…, G Erna, U Hoang, B Lina, S de Lusignan… - …, 2021 - eurosurveillance.org
Eurosurveillance | Low levels of respiratory syncytial virus activity in Europe during the 2020/21
season: what can we expect in the coming summer and autumn/winter? 1887 Other sites…
season: what can we expect in the coming summer and autumn/winter? 1887 Other sites…