[HTML][HTML] Treatment for mild chronic hypertension during pregnancy
Background The benefits and safety of the treatment of mild chronic hypertension (blood
pressure,< 160/100 mm Hg) during pregnancy are uncertain. Data are needed on whether a …
pressure,< 160/100 mm Hg) during pregnancy are uncertain. Data are needed on whether a …
[HTML][HTML] Labor induction versus expectant management in low-risk nulliparous women
WA Grobman, MM Rice, UM Reddy… - … England Journal of …, 2018 - Mass Medical Soc
Background The perinatal and maternal consequences of induction of labor at 39 weeks
among low-risk nulliparous women are uncertain. Methods In this multicenter trial, we …
among low-risk nulliparous women are uncertain. Methods In this multicenter trial, we …
Non-invasive prenatal measurement of the fetal genome
The vast majority of prenatal genetic testing requires invasive sampling. However, this poses
a risk to the fetus, so one must make a decision that weighs the desire for genetic …
a risk to the fetus, so one must make a decision that weighs the desire for genetic …
Noninvasive in vivo monitoring of tissue-specific global gene expression in humans
Circulating cell-free RNA in the blood provides a potential window into the health,
phenotype, and developmental programs of a variety of human organs. We used high …
phenotype, and developmental programs of a variety of human organs. We used high …
Factors that predict prematurity and preeclampsia in pregnancies that are complicated by systemic lupus erythematosus
EF Chakravarty, I Colón, ES Langen, DA Nix… - American journal of …, 2005 - Elsevier
OBJECTIVE: The purpose of this study was to describe the outcomes of a 10-year cohort of
pregnancies in patients with systemic lupus erythematosus and to evaluate clinical and …
pregnancies in patients with systemic lupus erythematosus and to evaluate clinical and …
[HTML][HTML] Bacterial flora-typing with targeted, chip-based Pyrosequencing
A Sundquist, S Bigdeli, R Jalili, ML Druzin, S Waller… - BMC microbiology, 2007 - Springer
Background The metagenomic analysis of microbial communities holds the potential to
improve our understanding of the role of microbes in clinical conditions. Recent, dramatic …
improve our understanding of the role of microbes in clinical conditions. Recent, dramatic …
[HTML][HTML] A trial of hyperimmune globulin to prevent congenital cytomegalovirus infection
Background Primary cytomegalovirus (CMV) infection during pregnancy carries a risk of
congenital infection and possible severe sequelae. There is no established intervention for …
congenital infection and possible severe sequelae. There is no established intervention for …
Microfluidic digital PCR enables rapid prenatal diagnosis of fetal aneuploidy
HC Fan, YJ Blumenfeld, YY El-Sayed, J Chueh… - American journal of …, 2009 - Elsevier
OBJECTIVE: The purpose of this study was to demonstrate that digital polymerase chain
reaction (PCR) enables rapid, allele independent molecular detection of fetal aneuploidy …
reaction (PCR) enables rapid, allele independent molecular detection of fetal aneuploidy …
Cesarean delivery on maternal request: wise use of finite resources? A view from the trenches
ML Druzin, YY El-Sayed - Seminars in perinatology, 2006 - Elsevier
Cesarean section rates are rising in the United States and were at an all time high of 29
percent in 2004. Within this context, the issue of cesarean section on maternal request has …
percent in 2004. Within this context, the issue of cesarean section on maternal request has …
[HTML][HTML] A randomized trial of intrapartum fetal ECG ST-segment analysis
MA Belfort, GR Saade, E Thom… - … England Journal of …, 2015 - Mass Medical Soc
Background It is unclear whether using fetal electrocardiographic (ECG) ST-segment
analysis as an adjunct to conventional intrapartum electronic fetal heart-rate monitoring …
analysis as an adjunct to conventional intrapartum electronic fetal heart-rate monitoring …