[HTML][HTML] Integrative microbiomics in bronchiectasis exacerbations
M Mac Aogain, JK Narayana, PY Tiew, NABM Ali… - Nature medicine, 2021 - nature.com
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …
colonization and infection. We present an approach to the multi-biome that integrates …
Obstructive sleep apnea and lung cancer: a systematic review and meta-analysis
Rationale: In 2020, lung cancer was the leading cause of cancer deaths and the most
common cancer in men. Although obstructive sleep apnea (OSA) has been postulated to be …
common cancer in men. Although obstructive sleep apnea (OSA) has been postulated to be …
Obstructive sleep apnea and cardiovascular events after percutaneous coronary intervention
Background—There is a paucity of data from large cohort studies examining the prognostic
significance of obstructive sleep apnea (OSA) in patients with coronary artery disease. We …
significance of obstructive sleep apnea (OSA) in patients with coronary artery disease. We …
[HTML][HTML] Conducting a high-stakes OSCE in a COVID-19 environment
K Boursicot, S Kemp, TH Ong, L Wijaya, SH Goh… - …, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic has presented significant challenges for medical schools. It is
critical to ensure final year medical school students are not delayed in their entry to the …
critical to ensure final year medical school students are not delayed in their entry to the …
Massive hemoptysis requiring intensive care
TH Ong, P Eng - Intensive care medicine, 2003 - Springer
Objectives. Massive hemoptysis can cause airway or hemodynamic compromise requiring
intensive care. We reviewed the management and outcome of this group of patients in our …
intensive care. We reviewed the management and outcome of this group of patients in our …
Simplifying STOP-BANG: use of a simple questionnaire to screen for OSA in an Asian population
TH Ong, S Raudha, S Fook-Chong, N Lew… - Sleep and Breathing, 2010 - Springer
Objective We aim to assess the utility of a simple-to-use 8-point questionnaire in screening
for moderate–severe obstructive sleep apnea (OSA) and to assess the validity of cutoffs …
for moderate–severe obstructive sleep apnea (OSA) and to assess the validity of cutoffs …
[PDF][PDF] Neisseria species as pathobionts in bronchiectasis
L Li, M Mac Aogain, T Xu, TK Jaggi, LLY Chan, J Qu… - Cell host & …, 2022 - cell.com
Neisseria species are frequently identified in the bronchiectasis microbiome, but they are
regarded as respiratory commensals. Using a combination of human cohorts, next …
regarded as respiratory commensals. Using a combination of human cohorts, next …
Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study
M Mac Aogáin, R Chandrasekaran… - European …, 2018 - Eur Respiratory Soc
Understanding the composition and clinical importance of the fungal mycobiome was
recently identified as a key topic in a “research priorities” consensus statement for …
recently identified as a key topic in a “research priorities” consensus statement for …
[HTML][HTML] Early prediction of high flow nasal cannula therapy outcomes using a modified ROX index incorporating heart rate
KJ Goh, HZ Chai, TH Ong, DW Sewa, GC Phua… - Journal of intensive …, 2020 - Springer
Background The ROX index (ratio of pulse oximetry/FIO 2 to respiratory rate) has been
validated to predict high flow nasal cannula therapy (HFNC) outcomes in patients with …
validated to predict high flow nasal cannula therapy (HFNC) outcomes in patients with …
Metagenomics reveals a core macrolide resistome related to microbiota in chronic respiratory disease
Rationale: Long-term antibiotic use for managing chronic respiratory disease is increasing;
however, the role of the airway resistome and its relationship to host microbiomes remains …
however, the role of the airway resistome and its relationship to host microbiomes remains …