Exploration versus exploitation in space, mind, and society
Search is a ubiquitous property of life. Although diverse domains have worked on search
problems largely in isolation, recent trends across disciplines indicate that the formal …
problems largely in isolation, recent trends across disciplines indicate that the formal …
[HTML][HTML] Therapeutic advances in COVID-19
N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
Over 2 years have passed since the start of the COVID-19 pandemic, which has claimed
millions of lives. Unlike the early days of the pandemic, when management decisions were …
millions of lives. Unlike the early days of the pandemic, when management decisions were …
A review of the technologies, economics and policy instruments for decarbonising energy-intensive manufacturing industries
Industrial processes account for one-third of global energy demand. The iron and steel,
cement and refining sectors are particularly energy-intensive, together making up over 30 …
cement and refining sectors are particularly energy-intensive, together making up over 30 …
Interleukin-6 receptor antagonists in critically ill patients with Covid-19–preliminary report
Remap-Cap Investigators, AC Gordon, PR Mouncey… - Medrxiv, 2021 - medrxiv.org
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis
P Domingo, I Mur, GM Mateo, M del Mar Gutierrez… - Jama, 2021 - jamanetwork.com
Importance Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …
[HTML][HTML] Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials
Substantial COVID-19 research investment has been allocated to randomized clinical trials
(RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or …
(RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or …
Optimal foraging in semantic memory.
Do humans search in memory using dynamic local-to-global search strategies similar to
those that animals use to forage between patches in space? If so, do their dynamic memory …
those that animals use to forage between patches in space? If so, do their dynamic memory …
Dopamine and glutamate control area-restricted search behavior in Caenorhabditis elegans
T Hills, PJ Brockie, AV Maricq - Journal of Neuroscience, 2004 - Soc Neuroscience
Area-restricted search (ARS) is a foraging strategy used by many animals to locate
resources. The behavior is characterized by a time-dependent reduction in turning …
resources. The behavior is characterized by a time-dependent reduction in turning …
In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity
The efficacy of vaccine adjuvants such as Toll-like receptor agonists (TLRa) can be
improved through formulation and delivery approaches. Here, we attached small molecule …
improved through formulation and delivery approaches. Here, we attached small molecule …
Animal foraging and the evolution of goal‐directed cognition
TT Hills - Cognitive science, 2006 - Wiley Online Library
Foraging‐and feeding‐related behaviors across eumetazoans share similar molecular
mechanisms, suggesting the early evolution of an optimal foraging behavior called area …
mechanisms, suggesting the early evolution of an optimal foraging behavior called area …