Transvaginal three‐dimensional ultrasound assessment of Sylvian fissures at 18–30 weeks' gestation

LC Poon, DS Sahota, P Chaemsaithong… - … in Obstetrics & …, 2019 - Wiley Online Library
Objective To (1) evaluate the normal development of the Sylvian fissures in the anterior
coronal view of the fetal brain at 18–30 weeks' gestation by transvaginal three‐dimensional …

[HTML][HTML] Clinical validation of fetal cfDNA analysis using rolling-circle-replication and imaging technology in Osaka (CRITO Study)

RK Pooh, C Masuda, R Matsushika, M Machida… - Diagnostics, 2021 - mdpi.com
Background: Noninvasive prenatal genetic testing (NIPT) has been adopted as the first
choice for aneuploidy screening. The purposes of this study were to investigate the accuracy …

Glucose lowering activity by oral administration of bis(allixinato)oxidovanadium(iv) complex in streptozotocin-induced diabetic mice and gene expression profiling in …

M Hiromura, Y Adachi, M Machida, M Hattori… - Metallomics, 2009 - academic.oup.com
Vanadyl (iv) complexes are anti-diabetogenic agents. Intra-peritoneal administration of bis
(allixinato) oxidovanadium (iv)[VO (alx) 2] lowers high blood glucose levels in animal …

Roles of adriamycin and adriamycin dimer in antitumor activity of the polymeric micelle carrier system

S Fukushima, M Machida, T Akutsu, K Shimizu… - Colloids and Surfaces B …, 1999 - Elsevier
Adriamycin (ADR) dimer was prepared and its antitumor activity was evaluated with mouse
colon adenocarcinoma 26 (C 26). As compared with original ADR, the dimer did not show …

Cat‐Ear‐Line: A Sonographic Sign of Cortical Development?

N Matsuzawa, LC Poon, M Machida… - … of Ultrasound in …, 2023 - Wiley Online Library
Objectives Diagonal echogenic lines outside the lateral ventricle have often been observed
in the anterior coronal planes of the normal fetal brain by neurosonography. We have …

[HTML][HTML] Fetal Megalencephaly with Cortical Dysplasia at 18 Gestational Weeks Related to Paternal UPD Mosaicism with PTEN Mutation

RK Pooh, M Machida, I Imoto, EN Arai, H Ohashi… - Genes, 2021 - mdpi.com
The phosphatase and tensin homolog (PTEN) gene is a tumor-suppressor gene located on
10q22-23. Since the introduction of molecular genetics in prenatal diagnostics, various birth …

Chronopharmacological analysis of antidepressant activity of a dual-action serotonin noradrenaline reuptake inhibitor (SNRI), milnacipran, in rats

H Kawai, M Machida, T Ishibashi, N Kudo… - Biological and …, 2018 - jstage.jst.go.jp
Biological rhythms are thought to be related to the pathogenesis and therapy of various
diseases including depression. Here we investigated the influence of circadian rhythms on …

Simultaneous determination of NK611, a novel water‐soluble derivative of etoposide, and its metabolite (DeNK611) in dog plasma by column‐switching high …

M Machida, S Tanaka… - Biomedical …, 1993 - Wiley Online Library
A simple, selective, reversed phase liquid chromatographic method using a column‐
switching technique has been developed for the simultaneous determination of a novel …

Cultivating design thinking skills through the biodesign process in Japan

H Kiriyama, T Kakihiana, Y Maeda… - BMJ …, 2022 - innovations.bmj.com
Background The biodesign process, which originated at Stanford University, has had a
significant impact on medical device invention. Design thinking skills are core elements in …

[PDF][PDF] Early Sonographic Findings for Suspecting de novo Single-gene Mutation

RK Pooh, M Machida, T Nakamura… - Donald Sch J …, 2020 - researchgate.net
Introduction: Currently, many obstetrics departments widely use prenatal genetic screening
tests in the first trimester, including noninvasive prenatal genetic tests (NIPT), sonographic …