User profiles for "author:Mark Santos"

Mark Santos

MilliporeSigma
Verified email at milliporesigma.com
Cited by 855

[HTML][HTML] Uptake and fate of extracellular membrane vesicles: nucleoplasmic reticulum-associated late endosomes as a new gate to intercellular communication

D Corbeil, MF Santos, J Karbanová, T Kurth, G Rappa… - Cells, 2020 - mdpi.com
Extracellular membrane vesicles (EVs) are emerging as new vehicles in intercellular
communication, but how the biological information contained in EVs is shared between cells …

Clinical significance of extracellular vesicles in plasma from glioblastoma patients

D Osti, M Del Bene, G Rappa, M Santos… - Clinical Cancer …, 2019 - AACR
Purpose: Glioblastoma (GBM) is the most common primary brain tumor. The identification of
blood biomarkers reflecting the tumor status represents a major unmet need for optimal …

[HTML][HTML] Extracellular vesicles from thyroid carcinoma: The new frontier of liquid biopsy

G Rappa, C Puglisi, MF Santos, S Forte… - International Journal of …, 2019 - mdpi.com
The diagnostic approach to thyroid cancer is one of the most challenging issues in oncology
of the endocrine system because of its high incidence (3.8% of all new cancer cases in the …

[HTML][HTML] VAMP-associated protein-A and oxysterol-binding protein–related protein 3 promote the entry of late endosomes into the nucleoplasmic reticulum

MF Santos, G Rappa, J Karbanová, T Kurth… - Journal of Biological …, 2018 - ASBMB
The endocytic pathway plays an instrumental role in recycling internalized molecules back
to the plasma membrane or in directing them to lysosomes for degradation. We recently …

Comparative analysis of innate immune system function in metastatic breast, colorectal, and prostate cancer patients with circulating tumor cells

MF Santos, VKR Mannam, BS Craft, LV Puneky… - … and molecular pathology, 2014 - Elsevier
In recent years, circulating tumor cells (CTCs) in metastatic cancer patients have been found
to be a promising biomarker to predict overall survival and tumor progression in these …

Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration

SA Boehme, SK Sullivan, PD Crowe… - The Journal of …, 1999 - journals.aai.org
Eotaxin is a potent eosinophil chemoattractant that plays an important role in regulating
eosinophil tissue levels both in healthy individuals and in diseases associated with …

[HTML][HTML] HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells

MF Santos, G Rappa, J Karbanová, P Diana… - Nature …, 2023 - nature.com
The mechanism of human immunodeficiency virus 1 (HIV-1) nuclear entry, required for
productive infection, is not fully understood. Here, we report that in HeLa cells and activated …

[HTML][HTML] Nuclear transport of cancer extracellular vesicle-derived biomaterials through nuclear envelope invagination-associated late endosomes

G Rappa, MF Santos, TM Green, J Karbanová… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Extracellular membrane vesicles (EVs) function as vehicles of intercellular communication,
but how the biomaterials they carry reach the target site in recipient cells is an open …

The impact of diabetes on outcomes after acute ischemic stroke: a prospective observational study

N Akhtar, S Kamran, R Singh, RA Malik, D Deleu… - Journal of Stroke and …, 2019 - Elsevier
Background: Stroke in diabetics may delay recovery and increases the risk of early
recurrence of stroke. We compared the outcomes of patients (with and without diabetes) …

Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells

TL Green, MF Santos, AA Ejaeidi, BS Craft… - … and molecular pathology, 2014 - Elsevier
The risk posed by breast cancer represents a complex interaction among factors affecting
tumor immunity of the host. Toll-like receptors (TLRs) are members of the innate immune …