Aortic root aneurysm formation is a cardinal feature of Marfan syndrome (MFS) and likely
TGF‐β driven via Smad (canonical) and ERK (non‐canonical) signalling. The current study …

Background Statins reduce aneurysm growth in mouse models of Marfan syndrome,
although the mechanism is unknown. In addition to reducing cholesterol, statins block …

OBJECTIVE Surgical videos are commonly utilized by trainees to prepare for surgical cases.
However, currently available videos tend to be of excessive length, variable quality, and …

As technology and access to information evolve, so must our techniques in surgical
education. The traditional surgical learning paradigm—consisting of textbook reading …

115.4 million individuals are projected to live with dementia by 2050. 1 Notably, there is
consensus that a substantial proportion of dementia cases may be preventable. 2 Therefore …

Objective: Our team set out to design and develop a low-cost 3D-printed liver transplant
simulator. Design: The simulator comprises a 3D-printed recipient body cavity and the filled …

Background Mindstep is an app that aims to improve dementia screening by assessing
cognition and risk factors. It considers important clinical risk factors, including prodromal …

Introduction Clinical simulators are an important resource for medical students seeking to
improve their fundamental surgical skills. Three-dimensional (3-D) printing offers an …

Introduction Low-density lipoprotein cholesterol (LDL) is a known contributing factor to
atherosclerotic cardiovascular disease (ASCVD) and a primary therapeutic target for …

DISCUSSION SVG aneurysms are rare but are being reported with greater frequency. 3
Whether this is due to alterations in technique, longer follow-up of patients undergoing …