Hemorrhagic transformation (HT) is a common complication of ischemic stroke that is
exacerbated by thrombolytic therapy. Methods to better prevent, predict, and treat HT are …

Neutrophils have key roles in ischemic brain injury, thrombosis, and atherosclerosis. As
such, neutrophils are of great interest as targets to treat and prevent ischemic stroke. After …

Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

MicroRNAs (miRNAs) regulate gene expression and have a critical role in many biologic
and pathologic processes. We hypothesized that miRNA expression profiles in injured brain …

Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia …

This review provides a summary of the protein and RNA biomarkers that have been studied
for the diagnosis and assessment of ischemic stroke. Many of the biomarkers identified …

Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

Importance The relative rates of detection of atrial fibrillation (AF) or atrial flutter from
evaluating patients with prolonged electrocardiographic monitoring with an external loop …

Background microRNA (miRNA) are important regulators of gene expression. In patients
with ischemic stroke we have previously shown that differences in immune cell gene …