User profiles for "author:Gerard Sheehan"
Gerard SheehanMaynooth University Verified email at mu.ie Cited by 907 |
Innate humoral immune defences in mammals and insects: The same, with differences?
G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …
of mammals and a wide range of insects is now employed to assess the virulence of …
Immune priming: the secret weapon of the insect world
G Sheehan, G Farrell, K Kavanagh - Virulence, 2020 - Taylor & Francis
Insects are a highly successful group of animals that inhabit almost every habitat and
environment on Earth. Part of their success is due to a rapid and highly effective immune …
environment on Earth. Part of their success is due to a rapid and highly effective immune …
[HTML][HTML] Galleria mellonella: The Versatile Host for Drug Discovery, In Vivo Toxicity Testing and Characterising Host-Pathogen Interactions
M Piatek, G Sheehan, K Kavanagh - Antibiotics, 2021 - mdpi.com
Larvae of the greater wax moth, Galleria mellonella, are a convenient in vivo model for
assessing the activity and toxicity of antimicrobial agents and for studying the immune …
assessing the activity and toxicity of antimicrobial agents and for studying the immune …
Increased platelet reactivity in HIV-1–infected patients receiving abacavir-containing antiretroviral therapy
CS Satchell, JA O'Halloran, AG Cotter… - Journal of Infectious …, 2011 - academic.oup.com
Background. Current or recent use of abacavir for treating human immunodeficiency virus
type 1 (HIV-1) infection has been associated with increased rates of myocardial infarction …
type 1 (HIV-1) infection has been associated with increased rates of myocardial infarction …
[HTML][HTML] The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest
K Kavanagh, G Sheehan - Journal of Fungi, 2018 - mdpi.com
The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …
Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans
G Sheehan, K Kavanagh - Virulence, 2018 - Taylor & Francis
Galleria mellonella larvae were administered an inoculum of Candida albicans and the
response to infection over 24 hours was monitored. The yeast cell density in infected larvae …
response to infection over 24 hours was monitored. The yeast cell density in infected larvae …
Investigating the effect of antiretroviral switch to tenofovir alafenamide on lipid profiles in people living with HIV
A Lacey, S Savinelli, EA Barco, A Macken, AG Cotter… - Aids, 2020 - journals.lww.com
Background: Whilst reporting improved renal and bone safety profiles, studies have noted
changes in lipid profiles among people living with HIV (PLWH) receiving antiretroviral …
changes in lipid profiles among people living with HIV (PLWH) receiving antiretroviral …
Seizure with CSF lymphocytosis as a presenting feature of COVID-19 in an otherwise healthy young man
S Lyons, B O'Kelly, S Woods, C Rowan… - … -European Journal of …, 2020 - seizure-journal.com
A 20-year old previously well man was brought to hospital following a seizure. For three
days he had complained of myalgia, lethargy and fever. On attempting to get out of bed at …
days he had complained of myalgia, lethargy and fever. On attempting to get out of bed at …
Utilization of Galleria mellonella larvae to characterize the development of Staphylococcus aureus infection
G Sheehan, A Dixon, K Kavanagh - Microbiology, 2019 - microbiologyresearch.org
Staphylococcus aureus is a human opportunistic pathogen that causes a wide range of
superficial and systemic infections in susceptible patients. Here we describe how an …
superficial and systemic infections in susceptible patients. Here we describe how an …
UtilisingGalleria mellonella larvae for studying in vivo activity of conventional and novel antimicrobial agents
M Piatek, G Sheehan, K Kavanagh - Pathogens and Disease, 2020 - academic.oup.com
The immune response of insects displays many structural and functional similarities to the
innate immune response of mammals. As a result of these conserved features, insects may …
innate immune response of mammals. As a result of these conserved features, insects may …