User profiles for "author:David Roberts"

David D. Roberts

- Verified email at mail.nih.gov - Cited by 35777

David J Roberts

- Verified email at ndcls.ox.ac.uk - Cited by 26719

David CS Roberts

- Verified email at wakehealth.edu - Cited by 17788

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a …

T Vos, RM Barber, B Bell, A Bertozzi-Villa, S Biryukov… - The lancet, 2015 - thelancet.com
Background Up-to-date evidence about levels and trends in disease and injury incidence,
prevalence, and years lived with disability (YLDs) is an essential input into global, regional …

The functional significance of social cognition in schizophrenia: a review

SM Couture, DL Penn, DL Roberts - Schizophrenia bulletin, 2006 - academic.oup.com
Deficits in a wide array of functional outcome areas (eg, social functioning, social skills,
independent living skills, etc) are marked in schizophrenia. Consequently, much recent …

Cross‐validation strategies for data with temporal, spatial, hierarchical, or phylogenetic structure

DR Roberts, V Bahn, S Ciuti, MS Boyce, J Elith… - …, 2017 - Wiley Online Library
Ecological data often show temporal, spatial, hierarchical (random effects), or phylogenetic
structure. Modern statistical approaches are increasingly accounting for such dependencies …

[HTML][HTML] SARS-CoV-2 evolution during treatment of chronic infection

SA Kemp, DA Collier, RP Datir, IATM Ferreira, S Gayed… - Nature, 2021 - nature.com
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
critical for virus infection through the engagement of the human ACE2 protein and is a major …

Genomic atlas of the human plasma proteome

BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley… - Nature, 2018 - nature.com
Although plasma proteins have important roles in biological processes and are the direct
targets of many drugs, the genetic factors that control inter-individual variation in plasma …

[PDF][PDF] The allelic landscape of human blood cell trait variation and links to common complex disease

WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa… - Cell, 2016 - cell.com
Many common variants have been associated with hematological traits, but identification of
causal genes and pathways has proven challenging. We performed a genome-wide …

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

JD Smith, CE Chitnis, AG Craig, DJ Roberts… - Cell, 1995 - cell.com
Plasmodium falciparum expresses on the host erythrocyte surface clonally variant antigens
and ligands that mediate adherence to endothelial receptors. Both are central to …

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization

DW Roberts, G Patlewicz, PS Kern… - Chemical Research …, 2007 - ACS Publications
The goal of eliminating animal testing in the predictive identification of chemicals with the
intrinsic ability to cause skin sensitization is an important target, the attainment of which has …

The chemical biology of nitric oxide: implications in cellular signaling

DD Thomas, LA Ridnour, JS Isenberg… - Free Radical Biology …, 2008 - Elsevier
Nitric oxide (NO) has earned the reputation of being a signaling mediator with many diverse
and often opposing biological activities. The diversity in response to this simple diatomic …

Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy

NR Richardson, DCS Roberts - Journal of neuroscience methods, 1996 - Elsevier
Drug self-administration studies have recently employed progressive ratio (PR) schedules to
examine psychostimulant and opiate reinforcement. This review addresses the technical …