BACKGROUND: Impaired perineal wound healing has become a significant clinical problem
after abdominoperineal resection for rectal cancer. The increased use of neoadjuvant …

Epidemiological studies have shown that the use of nonsteroid anti‐inflammatory drugs
(NSAIDs) is associated with reduced risk of gastric cancer. The best‐known target of NSAIDs …

Aim The introduction of anti‐tumour necrosis factor (anti‐TNF; infliximab and adalimumab)
has changed the management of Crohn's perianal fistula from almost exclusively surgical …

Innate lymphoid cells (ILCs) are effectors of innate immunity and regulators of tissue
modeling. Recently identified ILC populations have a cytokine expression pattern that …

Human group 1 ILCs consist of at least three phenotypically distinct subsets, including NK
cells, CD127+ ILC1, and intraepithelial CD103+ ILC1. In inflamed intestinal tissues from …

This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …

Adenocarcinoma of the esophagus, or GEJ, has a poor prognosis. Early lesions [ie high
grade dysplasia (HGD) or T1-carcinoma] are potentially curable. Local endoscopic therapies …

ECCO-ESCP Consensus on Surgery for Crohn’s Disease Page 1 Copyright © 2017
European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press …

Background Neoadjuvant chemoradiotherapy (CRT) has been proven to increase local
control in rectal cancer, but the optimal interval between CRT and surgery is still unclear …

BACKGROUND: Endoscopic techniques are being developed for the local treatment of early
stage esophageal cancer. However, such therapy is not appropriate for patients with lymph …