Voice is a collection of art, poetry and narratives created by women living with a history of substance use and addiction. The intent of this collection is to explore women's understanding of harm reduction, to challenge the effects of stigmatization and to explore the experiences of those who have historically been silenced or devalued. Voice was conceived by a group of Kamloops nurses who came together and used their knowledge of mainstream systems, aesthetic knowing, feminism and substance use to guide the development and implementation of this project. During weekly gatherings, women with histories of substance use and addiction worked alongside a nurse in the co-creation of artistic expressions. Gender sensitivity, trust, equality and respect were vital to the success of this process. A selection of the women's art was presented at several venues, including an International Conference on Drug Related Harm, a Nursing Conference and a local art gallery. The positive community response to the women's work contributed to feelings of great pride and enhanced the women's confidence in their ability to express themselves. Throughout this process, women had the opportunity to develop social networks and to become aware of the value that their creative knowledge has to the community in which they live. Gender sensitive programming that is inclusive, participative and promotes women's health is required to fully understand women's experience of substance use and addiction in relation to harm reduction. Participation in projects such as Voice supports and encourages women to make sense of the world they live in and encourages health-promoting activities. The promising outcomes of this project might well be developed by nurses in other settings to further promote the health of women who have traditionally been stigmatized.