Table 3

Lower 90% CI bound for PBE metric

VariableLower bound
Log AUC collagen−0.01
Log Cmax collagen−0.02
Log AUC ASP-arachidonic acid0.19*
Log Cmax ASP-arachidonic acid0.16*
Log AUC salicylate0.54*
Log Cmax salicylate0.44

  • *Outside of range allowable to enable assumption of bioequivalence.

  • ASP, aspirin; AUC, area under the curve; PBE, population bioequivalence.