Baseline clinical profile | | | | |
Age | 74 (±14) | 62 (±14) | 1.09 (1.035 to 1.151) | 0.001 |
Male | 38% | 65% | 0.34 (0.13 to 0.89) | 0.025 |
Hypertension | 84% | 79% | 1.44 (0.38 to 5.52) | 0.756 |
Hyperlipidaemia | 79% | 86% | 0.64 (0.18 to 2.24) | 0.491 |
Diabetes mellitus | 33% | 37% | 0.84 (0.29 to 2.49) | 0.764 |
Chronic kidney disease | 30% | 19% | 1.80 (0.59 to 5.46) | 0.360 |
Ischaemic heart disease | 42% | 41% | 1.05 (0.38 to 2.89) | 0.920 |
Smoking | 38% | 31% | 1.33 (0.29 to 6.13) | 0.500 |
Baseline echocardiographic profile | | | |
Left ventricular ejection fraction (%) | 66% (±10) | 65% (±11) | 1.013 (0.960 to 1.068) | 0.645 |
Pulmonary artery systolic pressure (mm Hg) | 34.4 (±6.7) | 32.9 (±8.5) | 1.023 (0.950 to 1.103) | 0.543 |
Left ventricular mass index (g/m2) | 115.11 (±41.95) | 99.18 (±31.90) | 1.012 (0.997 to 1.028) | 0.120 |
Other valvular lesions present | 19% | 19% | 0.95 (0.29 to 3.16) | 0.604 |