Footnotes

• Twitter @stumaitland

• Contributors SM is the lead author, guarantor, and prepared the manuscript based on experience performing research in Neuroinformatics, and utilising machine learning on a regular basis. PME contributed and reviewed the manuscript, provided perspective from Irish practice. RB is the senior author who reviewed the manuscript and directed patient involvement. Used experience as Digital Lead for NIHR North East/Cumbria to express pitfalls in clinical medicine.

• Funding SM is funded by the NIHR Newcastle Biomedical Research Centre awarded to the Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University.

• Competing interests None declared.

• Patient consent for publication Not required.

• Provenance and peer review Not commissioned; externally peer reviewed.