Subclinical ochronosis features in alkaptonuria: a cross-sectional study

Trevor Cox; Eftychia Eirini Psarelli; Sophie Taylor; Hannah Rose Shepherd; Mark Robinson; Gabor Barton; Alpesh Mistry; Federica Genovese; Daniela Braconi; Daniela Giustarini; Ranieri Rossi; Annalisa Santucci; Milad Khedr; Andrew Hughes; Anna Milan; Leah Frances Taylor; Elizabeth West; Nicolas Sireau; Jane Patricia Dillon; Nicholas Rhodes; James Anthony Gallagher; Lakshminarayan Ranganath

doi:10.1136/bmjinnov-2018-000324

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Diagnostics

Original research

Subclinical ochronosis features in alkaptonuria: a cross-sectional study

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Trevor Cox Molecular and Clinical Cancer Medicine, Liverpool University, Liverpool, UK PubMed articles Google scholar articles
Eftychia Eirini Psarelli LCTU, University of Liverpool, School of Life Sciences, Liverpool, UK PubMed articles Google scholar articles
Sophie Taylor Physiotherapy, Royal Liverpool University Hospital, Liverpool, Merseyside, UK PubMed articles Google scholar articles
Hannah Rose Shepherd Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK PubMed articles Google scholar articles
Mark Robinson School of Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK PubMed articles Google scholar articles
Gabor Barton School of Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK PubMed articles Google scholar articles
Alpesh Mistry Musculoskeletal Radiology, Royal Liverpool University Hospital, Liverpool, UK PubMed articles Google scholar articles
Federica Genovese Nordic Bioscience A/S, Herlev, Denmark PubMed articles Google scholar articles
Daniela Braconi Biotecnologie Chimica e Farmacia, Universita degli Studi di Siena Dipartimento di Biotecnologie Chimica e Farmacia, Siena, Italy PubMed articles Google scholar articles
Daniela Giustarini Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy PubMed articles Google scholar articles
Ranieri Rossi Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy PubMed articles Google scholar articles
Annalisa Santucci Biotecnologie Chimica e Farmacia, Universita degli Studi di Siena Dipartimento di Biotecnologie Chimica e Farmacia, Siena, Italy PubMed articles Google scholar articles
Milad Khedr Department of Clinical Chemistry and Metabolic Medicine, Royal Liverpool University Hospital, Liverpool, UK PubMed articles Google scholar articles
Andrew Hughes Clinical Biochemistry, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK PubMed articles Google scholar articles
Anna Milan Clinical Biochemistry, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK PubMed articles Google scholar articles
Leah Frances Taylor College of Clinical and Biomedical Science, University of Central Lancashire, Preston, UK PubMed articles Google scholar articles
Elizabeth West Dermatology, Royal Liverpool University Hospital, Liverpool, UK PubMed articles Google scholar articles
Nicolas Sireau AKU Society, Cambridge, UK PubMed articles Google scholar articles
Jane Patricia Dillon Musculoskeletal Biology, University of Liverpool, Institute of Ageing and Chronic Disease, Liverpool, UK PubMed articles Google scholar articles
Nicholas Rhodes Musculoskeletal Biology, University of Liverpool, Liverpool, UK PubMed articles Google scholar articles
James Anthony Gallagher Musculoskeletal Biology, University of Liverpool, Institute of Ageing and Chronic Disease, Liverpool, UK PubMed articles Google scholar articles
Lakshminarayan Ranganath Clinical Biochemistry and Metabolic Medicine, Royal Liverpool University Hospital, Liverpool, UK PubMed articles Google scholar articles

Correspondence to Dr Lakshminarayan Ranganath, Clinical Biochemistry and Metabolic Medicine, Royal Liverpool University Hospital, Liverpool L7 8XP, UK; lrang{at}liv.ac.uk

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Citation

Cox T, Psarelli EE, Taylor S, et al

Subclinical ochronosis features in alkaptonuria: a cross-sectional study

BMJ Innovations 2019;5:82-91.

Publication history

Received October 10, 2018
Revised April 4, 2019
Accepted August 11, 2019
First published September 28, 2019.

Online issue publication

December 30, 2019

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